Nos
Publications
EXPERTS EN UBIQUITINE-PROTÉASOME
Nous travaillons fort pour diffuser et faire connaitre nos résultats de recherche.
Publications du laboratoire
A short SUMOylation tag modulates transcription factor activity.
Bouchard AY, Vivet AJI, Cabana VC, Li C, Thibault P, Lussier MP, Mader S, Cappadocia L. J Biol Chem. 2025 Oct 8;301(11):110807.
doi: 10.1016/j.jbc.2025.110807.
RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons.
Cabana VC, Lussier MP. IBRO Neurosci Rep. 2025 Apr 9;18:559-573.
doi: 10.1016/j.ibneur.2025.04.004.
AP-1 contributes to endosomal targeting of the ubiquitin ligase RNF13 via a secondary and novel non-canonical binding motif
Cabana VC, Sénécal AM, Bouchard AY, Kourrich S, Cappadocia L, Lussier MP. J Cell Sci. 2024 Sep 15;137(18):jcs262035.
doi: 10.1242/jcs.262035
AI is a viable alternative to high throughput screening: a 318-target study
Atomwise AIMS Program. Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z. Erratum in: Sci Rep. 2024 Sep 16;14(1):21579.
doi: 10.1038/s41598-024-70321-w
Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection.
Lachance V, Bélanger SM, Hay C, Le Corvec V, Banouvong V, Lapalme M, Tarmoun K, Beaucaire G, Lussier MP, Kourrich S. Int J Mol Sci. 2023 Jan 19;24(3):1971.
doi: 10.3390/ijms24031971
Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167.
Ghilarducci K, Cabana VC, Harake A, Cappadocia L, Lussier MP. Int J Mol Sci. 2022 Jul 16;23(14):7847.
doi: 10.3390/ijms23147847
From Drosophila to Human: Biological Function of E3 Ligase Godzilla and Its Role in Disease.
Cabana VC, Lussier MP. Cells. 2022 Jan 23;11(3):380.
doi: 10.3390/cells11030380. Review.
RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association.
Cabana VC, Bouchard AY, Sénécal AM, Ghilarducci K, Kourrich S, Cappadocia L, Lussier MP. Cells. 2021 Nov 6;10(11):3063.
doi: 10.3390/cells10113063
Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor.
Ghilarducci K, Cabana VC, Desroches C, Chabi K, Bourgault S, Cappadocia L, Lussier MP. FEBS J. 2021 Mar 2.
doi: 10.1111/febs.15796
Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice.
Ve H, Cabana VC, Gouspillou G, Lussier MP. Neuroscience. 2020 Aug 21;442:100-113
doi: 10.1042/BCJ20170035
Identification of a conformational heparin-recognition motif on the peptide hormone secretin: key role for cell surface binding.
Quittot N, Nguyen PT, Nerée AT, Lussier MP, Bourgault S. Biochem J. 2017 Jun 26;474(13):2249-2260.
doi: 10.1042/BCJ20170035
Publications de Marc P. Lussier
GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.
Gu X, Mao X, Lussier MP, Hutchison MA, Zhou L, Hamra FK, Roche KW, Lu W. Nat Commun. 2016 Mar 2;7:10873. *Co-first authors.
doi: 10.1038/ncomms10873
Dynamic Regulation of N-Methyl-d-aspartate (NMDA) and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by Posttranslational Modifications.
Lussier MP, Sanz-Clemente A, Roche KW. J Biol Chem. 2015 Nov 27;290(48):28596-603.
doi: 10.1074/jbc.R115.652750
Casein kinase 2 phosphorylates GluA1 and regulates its surface expression.
Lussier MP, Gu X, Lu W, Roche KW. Eur J Neurosci. 2014 Apr;39(7):1148-58.
doi: 10.1111/ejn.12494
Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission.
Lussier MP, Herring BE, Nasu-Nishimura Y, Neutzner A, Karbowski M, Youle RJ, Nicoll RA, Roche KW. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19426-31.
doi: 10.1073/pnas.1217477109
Activity-dependent ubiquitination of the AMPA receptor subunit GluA2.
Lussier MP, Nasu-Nishimura Y, Roche KW. J Neurosci. 2011 Feb 23;31(8):3077-81.
doi: 10.1523/JNEUROSCI.5944-10.2011
TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling.
Mace KE, Lussier MP, Boulay G, Terry-Powers JL, Parfrey H, Perraud AL, Riches DW. J Cell Physiol. 2010 Nov;225(2):444-53.
doi: 10.1002/jcp.22221
The self-association of two N-terminal interaction domains plays an important role in the tetramerization of TRPC4.
Lepage PK, Lussier MP, McDuff FO, Lavigne P, Boulay G. Cell Calcium. 2009 Mar;45(3):251-9.
doi: 10.1016/j.ceca.2008.11.002
RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC.
Lussier MP, Lepage PK, Bousquet SM, Boulay G. Cell Calcium. 2008 May;43(5):432-43.
doi: 10.1016/j.ceca.2007.07.009
Identification of two domains involved in the assembly of transient receptor potential canonical channels.
Lepage PK, Lussier MP, Barajas-Martinez H, Bousquet SM, Blanchard AP, Francoeur N, Dumaine R, Boulay G. J Biol Chem. 2006 Oct 13;281(41):30356-64.
doi: 10.1074/jbc.M603930200
MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.
Lussier MP, Cayouette S, Lepage PK, Bernier CL, Francoeur N, St-Hilaire M, Pinard M, Boulay G. J Biol Chem. 2005 May 13;280(19):19393-400.
doi: 10.1074/jbc.M500391200
The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells.
Lessard CB, Lussier MP, Cayouette S, Bourque G, Boulay G. Cell Signal. 2005 Apr;17(4):437-45.
doi: 10.1016/j.cellsig.2004.09.005
Exocytotic insertion of TRPC6 channel into the plasma membrane upon Gq protein-coupled receptor activation.
Cayouette S, Lussier MP, Mathieu EL, Bousquet SM, Boulay G. J Biol Chem. 2004 Feb 20;279(8):7241-6.
doi: 10.1074/jbc.M312042200